Research Article|Articles in Press, 101824

Orthokeratology in adults and effect on quality of life

  • QianGeMai Ren
    Corresponding author.
    Department of Optometry and Vision Sciences, West China School of Medicine, Sichuan University Chengdu, China

    Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu, China
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  • Bi Yang
    Department of Optometry and Vision Sciences, West China School of Medicine, Sichuan University Chengdu, China

    Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu, China
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  • LongQian Liu
    Department of Optometry and Vision Sciences, West China School of Medicine, Sichuan University Chengdu, China

    Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu, China
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  • Pauline Cho
    School of Optometry, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China
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Published:March 09, 2023DOI:



      To determine changes in various ocular parameters of adults wearing orthokeratology (ortho-k) lenses and their levels of satisfaction and quality of life (QoL) after commencing treatment.


      Adults aged 18–38 years, with mild to moderate myopia and astigmatism < 1.50D, were wearing ortho-k lenses for one year. Data collection, which included history taking, refraction, axial length (AL), corneal topography, corneal biomechanics, and biomicroscopy examination, was performed at baseline and every 6 months during the study period. The level of satisfaction with the treatment and QoL was determined via questionnaires.


      Forty-four subjects completed the study. AL was shortened significantly at the 12-month visit: AL −0.03 (-0.45 to 0.13) mm compared to baseline (p < 0.05). A significant number of subjects in both groups presented with overall and central corneal staining, but the majority were mild (Grade 1). Central endothelial cell density was reduced by 40/mm2 (loss rate 1.4 %) (p < 0.05). High scores were obtained in the satisfaction questionnaire, with no significant differences between visits. At the 12-month visit, NEI-RQL-42 total score, dependence on correction, activity limitation, appearance, and satisfaction with the treatment all significantly increased compared to baseline values.


      Results suggest that ortho-k can be an effective and safe myopia correction technique for adults with low to moderate myopia, improving daytime vision without serious adverse events. Satisfaction with ortho-k lens wear was high, particularly those who were dependent on vision correction and found spectacles or contact lenses limiting specific activities or cosmetically undesirable.


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