Why measure central corneal thickness to confirm a diagnosis of glaucoma?

    Published:November 03, 2022DOI:
        In life there are chance meetings with various people, sometimes lifelong friendships are forged from these meetings. In 1994, Shehzad Naroo was undertaking a master’s degree at the University of Manchester Institute of Science and Technology (UMIST) and Sunil Shah was training as an ophthalmologist at the Manchester Royal Eye Hospital. They met in London, at the Optimax clinic on Finchley Road. Sunil was waiting to meet other surgical colleagues to discuss working for Optimax as one of their new laser refractive surgeons in the new clinic in Manchester, as he was keen to get access to their data for research. Shehzad was waiting to meet optometric colleagues with the view of starting work at the Manchester Optimax clinic, to see post-operative refractive surgery patients, linked to his research work, which continued into his PhD and beyond. They met in London, but both lived in Manchester, only a few miles apart, and worked at places that were a few minutes apart. Sunil was good friends with Anupam Chatterjee, a fellow ophthalmologist from the Manchester Royal Eye Hospital, who was already working with Optimax as a laser refractive surgeon. The three became good friends, a friendship that has lasted many years.
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          • Chatterjee A.
          • Shah S.
          • Bessant D.A.
          • Naroo S.A.
          • Doyle S.J.
          Reduction in intraocular pressure after excimer laser photorefractive keratectomy. Correlation with pretreatment myopia.
          Ophthalmology. 1997; 104: 355-359
          • Goldmann H.
          Studies on the starting pressure of aqueous humor in humans.
          Med Hyg (Geneve). 1946; 4: 8
          • Goldmann H.
          Clinical methods for the examination of intraocular pressure and discharge conditions in primary glaucoma.
          Ophthalmologica. 1960; 139: 214-238
          • Goldmann H.
          Factors influencing intraocular pressure.
          Bibl Ophthalmol. 1970; 81: 97-105
          • Harris J.E.
          • Gehrsitz L.
          • Gruber L.
          The hydration of the cornea. II. The effect of the intraocular pressure.
          Am J Ophthalmol. 1956; 42: 325-329
          • Ehlers N.
          • Bramsen T.
          • Sperling S.
          Applanation tonometry and central corneal thickness.
          Acta Ophthalmol. 1975; 53: 652-659
          • Whitacre M.M.
          • Stein R.
          Sources of error with use of Goldmann-type tonometers.
          Surv Ophthalmol. 1993; 38: 1-30
          • Shah S.
          • Chatterjee A.
          • Mathai M.
          • Kelly S.P.
          • Kwartz J.
          • Henson D.
          • et al.
          Relationship between corneal thickness and measured intraocular pressure in a general ophthalmology clinic.
          Ophthalmology. 1999; 106: 2154-2160
          • Bhan A.
          • Browning A.C.
          • Shah S.
          • Hamilton R.
          • Dave D.
          • Dua H.S.
          Effect of corneal thickness on intraocular pressure measurements with the pneumotonometer, Goldmann applanation tonometer, and Tono-Pen.
          Invest Ophthalmol Vis Sci. 2002; 43: 1389-1392
          • Shah S.
          Accurate intraocular pressure measurement-the myth of modern ophthalmology?.
          Ophthalmology. 2000; 107: 1805-1807
          • Mohamed S.
          • Shah S.
          Corneal thickness in primary care–should we all measure it?.
          Cont Lens Anterior Eye. 2008; 31: 109-111
          • Bhatt N.
          • Bhojwani R.
          • Morrison A.
          • Kwartz J.
          • Laiquzzaman M.
          • Shah S.
          A 10-year follow up of ocular hypertensive patients within the Bolton Corneal Thickness Study. Can measured factors predict prognostic outcomes?.
          Cont Lens Anterior Eye. 2008; 31: 147-153