Abstract
Objectives
The study aimed to assess the possible effects of corneal cross-linking (CXL) on contact
lens (CL) fitting in patients with progressive keratoconus who initially had CL intolerance.
Methods
A retrospective review was performed of the medical records of patients who had stopped
CL wear due to discomfort prior to CXL and who were fitted with CLs after CXL. All
eyes were evaluated pre- and 1, 6, 12, 24 months postoperatively. Data collected included
pre- and post-CXL refraction, corneal topographic data, uncorrected visual acuity,
and best-corrected visual acuity (BCVA). CL comfort was evaluated using the Likert scale post-CXL.
Results
A total of 20 eyes from 14 patients were included in the study. Preoperative Kmax
values significantly decreased by 2.8 D at 6 months and by 4.1 D at 12 months after
CXL (p < 0.001 for both). CLs were prescribed on average 12 ± 2.5 months after CXL.
The mean duration of successful CL wear was 10.4 ± 2.8 months during the follow-up
period. Subjective CL comfort scores were satisfactory post-CXL.
Conclusion
CXL not only halts the progression of keratoconus but may also improve CL tolerance
by providing a more regular shaped cornea in these patients. Ongoing corneal topographic
changes in the late postoperative period after CXL may have a positive effect on CL
fitting.
Keywords
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References
- Keratoconus.Surv Ophthalmol. 1998; 42: 297-319
- Contact lens in keratoconus.Indian J Ophthalmol. 2013; 61: 410-415
- Contact lens management of keratoconus.Clin Exp Optom. 2015; 98: 299-311
- Biomicroscopic signs and disease severity in keratoconus. Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study Group.Cornea. 1996; 15: 139-146
Wollensak G, Spoerl E, Seiler T. Riboflavin/ultraviolet-A-induced collagen crosslinking for the treatment of keratoconus. Am J Ophthalmol 2003;135:620e7.
- Crosslinking treatment of progressive keratoconus: new hope.Curr Opin Ophthalmol. 2006; 17: 356-360
- Flattening of the cornea after collagen crosslinking for keratoconus.J Cataract Refract Surg. 2011; 37: 1488-1492
- Collagen cross linking in the treatment of corneal ectatic diseases – Review.Turk J Ophthalmol. 2009; 39: 153-160
- Corneal topography indices after corneal collagen crosslinking for keratoconus and corneal ectasia: one-year results.J Cataract Refract Surg. 2011; 37: 1282-1290
- Alterations in contact lens fitting parameters following cross-linking in keratoconus patients of indian ethnicity.Int Ophthalmol. 2018; 38: 1521-1530
- Changes in corneal topography and biomechanical properties after collagen cross linking for keratoconus: 1-year results.Middle East Afr J Ophthalmol. 2015; 22: 212-219
- Contact lens fitting after corneal collagen cross-linking.Oman J Ophthalmol. 2019; 12: 177-180
- Effect of corneal cross-linking on contact lens tolerance in keratoconus.Clin Exp Optom. 2017; 100: 369-374
- Influence of contact lens wear on the results of ultraviolet A/riboflavin cross-linking for progressive keratoconus.Br J Ophthalmol. 2011; 95: 1402-1405
- Effect of corneal collagen cross-linking on corneal innervation, corneal sensitivity and tear function of patients with keratoconus.Ophthalmology. 2013; 120: 917-922
Keratoconus soft contact lenses, in: SwissLens product document, 2012, pp. 16–17.
- Rigid gas-permeable contact lens related life quality in keratoconic patients with different grades of severity.Clin Exp Optom. 2015; 98: 150-154
- A randomized, controlled trial of corneal collagen cross-linking in progressive keratoconus: three-year results.Ophthalmology. 2014; 121: 812-821
- Clinical evaluation of different types of contact lenses in keratoconus management.Cont Lens Anterior Eye. 2019; 42: 482-486
- Changes of corneal topography indices after CXL in progressive keratoconus assessed by Scheimpflug camera.J Refract Surg. 2014; 30: 374-378
- Long-term follow-up of corneal collagen cross-linking for keratoconus–the Cretan study.Cornea. 2014; 33: 1071-1079
- Variables affecting rigid contact lens comfort in the collaborative longitudinal evaluation of keratoconus (CLEK) study.Optom Vis Sci. 2004; 81: 182-188
- Complication and failure rates after corneal crosslinking.J Cataract Refract Surg. 2009; 35: 1358-1362
- Collagen cross-linking for advanced progressive keratoconus.Cornea. 2013; 32: 903-906
- The outcome of corneal collagen cross-linking in patients with advanced progressive keratoconus: a 2-year follow-up study.Middle East Afr J Opthalmol. 2019; 26: 11-16
- Corneal cross-linking with hypo-osmolar riboflavin solution in thin keratoconic corneas.Am J Ophthalmol. 2011; 152: 28-32
- Outcome of corneal collagen cross-linking in keratoconus: introducing the predictive factors.J Curr Ophthalmol. 2020; 32: 19-25
- The effect of corneal cross-linking on the anterior and posterior parameters of the cornea: a prospective repeatability study.Rom J Ophthalmol. 2019; 63: 68-74
Article info
Publication history
Published online: August 03, 2021
Accepted:
July 7,
2021
Received in revised form:
July 3,
2021
Received:
December 7,
2020
Identification
Copyright
© 2021 Published by Elsevier Ltd on behalf of British Contact Lens Association.