Intrasession repeatability of corneal, limbal and scleral measurements obtained with a fourier transform profilometer

  • Laurent Bataille
    Affiliations
    Group of Optics and Visual Perception. Department of Optics, Pharmacology and Anatomy, University of Alicante, Spain
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  • Ainhoa Molina-Martin
    Affiliations
    Group of Optics and Visual Perception. Department of Optics, Pharmacology and Anatomy, University of Alicante, Spain
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  • David P Piñero
    Correspondence
    Corresponding author at: Department of Optics, Pharmacology and Anatomy, University of Alicante, Crta San Vicente del Raspeig s/n 03690, San Vicente del Raspeig, Alicante, Spain.
    Affiliations
    Group of Optics and Visual Perception. Department of Optics, Pharmacology and Anatomy, University of Alicante, Spain

    Department of Ophthalmology, Vithas Medimar International Hospital, Alicante, Spain
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Published:November 23, 2020DOI:https://doi.org/10.1016/j.clae.2020.11.002

      Abstract

      Purpose

      To evaluate the intrasession repeatability of corneal, limbal and scleral measurements obtained by an experienced operator with a Fourier transform profilometer in healthy eyes.

      Methods

      Prospective, single-center study including 35 eyes of 35 participants with ages ranging from 13 to 52 years. All patients underwent three consecutive corneoscleral topographic evaluations with the Eye Surface Profiler (ESP) system (Eaglet Eye b.v.). Intrasession repeatability was analyzed for different geometric and sagittal height variables using the following parameters: the within-subject standard deviation (Sw) of the three consecutive measurements, intrasubject precision (1.96 × Sw), coefficient of variation (CV) and the intraclass correlation coefficient (ICC).

      Results

      Inner best fit sphere (BFS) showed good repeatability, with ICC of 0.844. Higher variability was observed for the repeated measurements of limbus and outer BFS, with ICCs of 0.636 and 0.739, respectively. For mean corneal and scleral radius, ICCs were 0.933 and 0.888, respectively. The repeatability of all sagittal height data was good for all chords evaluated (11–15 mm), with Sw values from 0.02 to 0.11 mm, and ICCs from 0.568 to 0.909. A significant positive correlation was found between the magnitude of temporal-nasal sagittal height difference for all measured chords and its Sw associated.

      Conclusion

      The ESP system can provide consistent measurements of sagittal height data for different chord diameters as well as for mean corneal and scleral radius in healthy eyes. Best fit approaches for limbal and scleral areas were less repeatable, although within a clinically acceptable range.

      Keywords

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