Abstract
Purpose
To evaluate differences in corneoscleral shape in keratoconus patients with and without
specialty lenses compared to controls.
Methods
A cross-sectional study was performed comparing three groups of keratoconus eyes:
24 lens-naïve keratoconus eyes (17 patients; group 1), 7 eyes with corneal lens wear
(7 patients; group 2) and 7 eyes with scleral lens wear (7 patients; group 3). For
comparison, 25 eyes of 25 emmetropic participants and 11 eyes of 11 astigmatic participants
were included. Corneoscleral topography measurements taken with the Eye Surface Profiler
(ESP, Eaglet Eye BV, Houten, Netherlands) were exported and assessed using custom-made
software to demarcate the limbal radius, and to calculate sagittal height and corneoscleral
asymmetry.
Results
In non-lens wearing keratoconus patients, sagittal height was found to be significantly
larger than in control eyes, in both the corneal periphery and sclera (paired t-test, pairwise comparisons p < 0.01). The level of peripheral corneal and scleral
asymmetry was also significantly higher in non-lens wearing keratoconus eyes compared
to controls (t-test, p < 0.01). Both corneal and scleral lens wear resulted in significant changes
to the shape of the corneal periphery and sclera. In all 3 groups of keratoconus eyes,
asymmetry of the peripheral cornea showed a very strong correlation with scleral asymmetry
(R2 = 0.90, 0.86 and 0.85 for groups 1–3, respectively).
Conclusion
The corneal periphery and sclera have a distinctly different shape in keratoconus
eyes compared to controls. Specialty lens wear induces significant regional changes
to the shape of the anterior eye in keratoconus eyes.
Keywords
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Article info
Publication history
Published online: June 08, 2020
Accepted:
June 3,
2020
Received in revised form:
May 25,
2020
Received:
April 19,
2020
Identification
Copyright
© 2020 British Contact Lens Association. Published by Elsevier Ltd. All rights reserved.
