Research Article| Volume 43, ISSUE 6, P609-612, December 2020

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Intraocular pressure changes in neophyte scleral lens wearers: A prospective study



      To examine the variation in intraocular pressure (IOP) during the first six months of scleral lens wear.


      Thirty-two neophyte scleral lens wearers were recruited and IOP was measured using Goldman applanation tonometry before, and after 1 and 6 months of scleral lens wear (following lens removal). All scleral lenses were designed based on scleral topography or an impression of the ocular surface. Central corneal thickness and the central post-lens fluid reservoir thickness were quantified using optical coherence tomography.


      Post-lens removal IOP displayed an increasing trend after 1 and 6 months of lens wear, but the magnitude of change was not clinically or statistically significant using several repeated measures analyses to account for sporadic missing longitudinal data (mean increase of 1 mmHg or less, p > 0.05). Central corneal thickness and the central post-lens fluid reservoir remained stable throughout the first six months of lens wear.


      IOP measured following lens removal did not vary significantly during the first 6 months of lens wear in scleral lens neophytes. Further research is required to determine if IOP varies during lens wear, following lens removal, or after longer-term lens wear due to suction forces or tissue compression beneath the landing zone.


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        • McMonnies C.W.
        A hypothesis that scleral contact lenses could elevate intraocular pressure.
        Clin Exp Optom. 2016; 99: 594-596
        • Miller D.
        • Carroll J.M.
        • Holmberg A.
        Scleral lens cling measurement.
        Am J Ophthalmol. 1968; 65: 929-930
        • Pearson R.M.
        Re: A hypothesis that scleral contact lenses could elevate intraocular pressure.
        Clin Exp Optom. 2017; 100: 103-104
        • Elving-Kokke K.H.
        • Sas-Meertens M.A.V.
        • de Beer F.M.
        • van Rijn L.J.
        • de Boer J.H.
        • Visser E.S.
        The treatment of ocular hypotony after trabeculectomy with a scleral lens: A case series.
        Cont Lens Anterior Eye. 2019; 42: 123-126
        • Jessen G.N.
        Physiological considerations in the design of internal and external surfaces of fluidless scleral contact lenses.
        Am J Optom Arch Am Acad Optom. 1969; 46: 308-311
        • Huggert A.
        The intraocular pressure in glaucomatous eyes, following the use of contact lenses.
        Acta Ophthalmol. 1953; 31: 141-152
        • Huggert A.
        Increase of the intraocular pressure when using contact glasses.
        Acta Ophthalmol. 1951; 29: 475-481
        • Cheung S.Y.
        • Collins M.J.
        • Vincent S.J.
        The impact of short-term fenestrated scleral lens wear on intraocular pressure.
        Cont Lens Anterior Eye. 2020; (In press)
        • Michaud L.
        • Samaha D.
        • Giasson C.J.
        Intra-ocular pressure variation associated with the wear of scleral lenses of different diameters.
        Cont Lens Anterior Eye. 2019; 42: 104-110
        • Nau C.B.
        • Schornack M.M.
        • McLaren J.W.
        • Sit A.J.
        Intraocular pressure after 2 hours of small-diameter scleral Lens Wear.
        Eye Contact Lens. 2016; 42: 350-353
        • Vincent S.J.
        • Alonso-Caneiro D.
        • Collins M.J.
        Evidence on scleral contact lenses and intraocular pressure.
        Clin Exp Optom. 2017; 100: 87-88
        • Aitsebaomo A.P.
        • Wong-Powell J.
        • Miller W.
        • Amir F.
        Influence of scleral lens on intraocular pressure.
        J Contact Lens Res Sci. 2019; 3: e1-e9
        • Shahnazi K.C.
        • Isozaki V.L.
        • Chiu G.B.
        Effect of scleral lens wear on central corneal thickness and intraocular pressure in patients with ocular surface disease.
        Eye Contact Lens. 2019; (In press)
        • Porcar E.
        • Montalt J.C.
        • Espana-Gregori E.
        • Peris-Martinez C.
        Impact of corneoscleral contact lens usage on corneal biomechanical parameters in keratoconic eyes.
        Eye Contact Lens. 2019; 45: 318-323
        • Fisher D.
        • Collins M.J.
        • Vincent S.J.
        Anterior segment optical coherence tomography scanning protocols and corneal thickness repeatability.
        Cont Lens Anterior Eye. 2019; (In press)
        • Armstrong R.A.
        Statistical guidelines for the analysis of data obtained from one or both eyes.
        Ophthalmic Physiol Opt. 2013; 33: 7-14
        • Nguyen B.A.
        • Reilly M.A.
        • Roberts C.J.
        Biomechanical contribution of the sclera to dynamic corneal response in air-puff induced deformation in human donor eyes.
        Exp Eye Res. 2020; 191107904
        • Nguyen B.A.
        • Roberts C.J.
        • Reilly M.A.
        Biomechanical impact of the sclera on corneal deformation response to an air-puff: a finite-element study.
        Front Bioeng Biotechnol. 2018; 6: 210
        • Yang K.
        • Xu L.
        • Fan Q.
        • Zhao D.
        • Ren S.
        Repeatability and comparison of new Corvis ST parameters in normal and keratoconus eyes.
        Sci Rep. 2019; 9: 15379
        • Vincent S.J.
        • Alonso-Caneiro D.
        • Collins M.J.
        • Beanland A.
        • Lam L.
        • et al.
        Hypoxic corneal changes following eight hours of scleral contact lens wear.
        Optom Vis Sci. 2016; 93: 293-299
        • Vincent S.J.
        • Alonso-Caneiro D.
        • Collins M.J.
        Corneal changes following short-term miniscleral contact lens wear.
        Cont Lens Anterior Eye. 2014; 37: 461-468
        • Tan B.
        • Tse V.
        • Kim Y.H.
        • Lin K.
        • Zhou Y.
        • Lin M.C.
        Effects of scleral-lens oxygen transmissibility on corneal thickness: a pilot study.
        Cont Lens Anterior Eye. 2019; 42: 366-372
        • Esen F.
        • Toker E.
        Influence of apical clearance on mini-scleral Lens settling, clinical performance, and corneal thickness changes.
        Eye Contact Lens. 2017; 43: 230-235
        • Ogbuehi K.C.
        • Chijuka J.C.
        • Osuagwu U.L.
        Changes in central corneal thickness values after instillation of oxybuprocaine hydrochloride 0.4%.
        Cont Lens Anterior Eye. 2012; 35: 199-202
        • Kim Y.H.
        • Tan B.
        • Lin M.C.
        • Radke C.J.
        Central corneal edema with scleral-lens wear.
        Curr Eye Res. 2018; 43: 1305-1315
        • Macedo-de-Araujo R.J.
        • Amorim-de-Sousa A.
        • van der Worp E.
        • et al.
        Clinical findings and ocular symptoms over 1 year in a sample of scleral Lens wearers.
        Eye Contact Lens. 2019; (In press)
        • Sng C.C.
        • Ang M.
        • Barton K.
        Central corneal thickness in glaucoma.
        Curr Opin Ophthalmol. 2017; 28: 120-126
        • Rathi V.M.
        • Mandathara P.S.
        • Dumpati S.
        • Sangwan V.S.
        Change in vault during scleral lens trials assessed with anterior segment optical coherence tomography.
        Cont Lens Anterior Eye. 2017; 40: 157-161
        • Vincent S.J.
        • Alonso-Caneiro D.
        • Collins M.J.
        The temporal dynamics of miniscleral contact lenses: Central corneal clearance and centration.
        Cont Lens Anterior Eye. 2018; 41: 162-168
        • Otchere H.
        • Jones L.W.
        • Sorbara L.
        Effect of time on scleral lens settling and change in corneal clearance.
        Optom Vis Sci. 2017; 94: 908-913
        • Kauffman M.J.
        • Gilmartin C.A.
        • Bennett E.S.
        • Bassi C.J.
        A comparison of the short-term settling of three scleral lens designs.
        Optom Vis Sci. 2014; 91: 1462-1466
        • Bier N.
        Contact lens routine and practice.
        Butterworths Scientific Publications, London1957