Highlights
- •Midday fogging was reported by 26 % of patients in a sample of established scleral lens wearers.
- •Midday fogging was not associated with age, sex, or race/ethnicity.
- •Indications for scleral lens wear were not predictive of midday fogging.
- •Neither specific lens designs (diameter or haptic design) nor care products were associated with midday fogging.
- •Patients who reported redness or irritation with scleral lens wear more commonly reported midday fogging.
Abstract
Purpose
To estimate the prevalence of patient-reported midday fogging and to identify risk
factors for midday fogging.
Method
A multicenter, cross-sectional study was conducted with an electronic survey that
was distributed to scleral lens practitioners. The survey asked them to describe their
most recently examined established scleral lens patient. Respondents provided data
about patient-reported midday fogging, patient demographic characteristics, indication
for lens wear, lens-wearing schedule, lens design, and care products.
Results
Of the 248 survey respondents who indicated whether their patients had midday fogging,
64 (25.8 %) had patients who self-reported such issues. Midday fogging was not associated
with demographic characteristics (age, sex, race/ethnicity), indications for scleral
lens wear, mean lens diameter (P = .30), haptic design (P = .29), use of a daily cleaner (P = .12), disinfection/storage solution used (P = .71), or filling solution (P = .65). Patients who reported midday fogging more commonly reported redness or irritation
associated with scleral lens wear compared with those who did not experience midday
fogging (P = .03).
Conclusions
Prevalence of midday fogging in this study was similar to previously reported rates.
No specific lens design or care product was associated with patient-reported midday
fogging. If inflammatory mediators are elevated in the postlens fluid reservoir of
patients with midday fogging, as previously described, the redness or irritation associated
with scleral lens wear suggests that ocular surface inflammation may be contributing
to this phenomenon.
Abbreviations:
MDF (midday fogging), MMP (matrix metalloproteinase), REDCap (Research Electronic Data Capture), TIMP (tissue inhibitor of metalloproteinases)Keywords
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Article info
Publication history
Published online: March 20, 2020
Accepted:
March 11,
2020
Received in revised form:
March 10,
2020
Received:
January 2,
2020
Footnotes
☆Data presented in this paper have been presented, in part, at the ARVO annual meeting, Vancouver, BC, May 2, 2019.
Identification
Copyright
© 2020 British Contact Lens Association. Published by Elsevier Ltd. All rights reserved.
