To investigate the effect of orthokeratology (OK) lens on axial length (AL) elongation in unilateral myopia and bilateral myopia with anisometropia children.
Twenty-seven unilateral myopia (group 1) and 25 bilateral myopia with anisometropia children (group 2) were involved in this 1-year retrospective study. The eyes with higher spherical equivalent refractive error (SER) were assigned to the H eyes subgroup and the fellow eyes with lower SER to the L eyes subgroup in the two groups.
The mean change in AL of H eyes and L eyes were 0.11 ± 0.19 mm, 0.30 ± 0.28 mm in group 1 (P = 0.04) and 0.09± 0.14mm, 0.13± 0.16mm in group 2 (P = 0.36), respectively. Multivariate regression analyses showed that significant difference of change in AL was found between H eyes and L eyes in group1 (β=0.25, P = 0.03), but no difference in group 2 (β=0.09, P = 0.12). The AL of H eyes in group 1 and group 2, H eyes in group 1 and L eyes in group 2 had the same increased rate (β= −0.04, P = 0.43; β = 0.02, P = 0.56).
Monocular OK lens is effective on suppression AL elongation of the myopic eyes and reduce anisometropia value in unilateral myopic children. The OK lens can control the AL elongation in both eyes at the same rate, but it cannot reduce anisometropia value in bilateral myopia with anisometropia children after 1-year follow-up.
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- Profile of anisometropia and aniso-astigmatism in children: prevalence and association with age, ocular biometric measures, and refractive status.Invest Ophthalmol Vis Sci. 2013; 54: 602-608
- Stereoacuity after wave front-guided photorefractive keratectomy in anisometropia.J Ophthalmic Vis Res. 2017; 12: 265-269
- Effects of aniseikonia, anisometropia, accommodation, retinal illuminance, and pupil size on stereopsis.Invest Ophthalmol Vis Sci. 1985; 26: 741-750
- Anisometropia in children from infancy to 15 years.Invest Ophthalmol Vis Sci. 2012; 53: 3782-3787
- The prevalence of anisometropia, amblyopia and strabismus in schoolchildren of Shiraz, Iran.Strabismus. 2010; 18: 104-110
- Anisometropia of spherical equivalent and astigmatism among myopes: a 23-year follow-up study of prevalence and changes from childhood to adulthood.Acta Ophthalmol. 2017; 95518e24
- Myopic anisometropia: ocular characteristics and aetiological considerations.Clin Exp Optom. 2014; 97: 291-307
- Effect of myopic anisometropia on anterior and posterior ocular segment parameters.Int Ophthalmol. 2017; 37: 377-384
- Clinical characteristics of unilateral myopic anisometropia in a juvenile optometric practice population.Ophthalmic Physiol Opt. 2004; 24: 458-463
- Assessing the change of anisometropia in unilateral myopic children receiving monocular orthokeratology treatment.J Formos Med Assoc. 2019; 118: 1122-1128
- Stereoacuity after wave-front guided photorefractive keratectomy in anisometropia.J Ophthalmic Vis Res. 2017; 12: 265-269
- The use of rigid gas permeable contact lenses in children with myopic amblyopia: a case series.Contact Lens Anterior Eye. 2018; 41: 224-228
- Orthokeratology lens for management of myopia in anisometropic children: a contralateral study.Cont Lens Anterior Eye. 2019; 3 (pii: S1367-0484, 30959-30957)
- Effect of Orthokeratology on axial length elongation in anisomyopic children.Optom Vis Sci. 2019; 96: 43-47
- Asymmetrical increase in axial length in the two eyes of a monocular orthokeratology patient.Optom Vis Sci. 2004; 81: 653-656
- Progressive anisometropia and orthokeratology: a case report.Clin Exp Optom. 2018; 101: 599-600
- Shanghai Orthokeratology Study (SOS) Group. Effects of orthokeratology on axial length growth in myopic anisometropes.Cont Lens Anterior Eye. 2018; 41: 263-266
- Retardation of myopia in orthokeratology (ROMIO) study: a 2-year randomized clinical trial.Invest Ophthalmol Vis Sci. 2012; 53: 7077-7085
- Myopia control with orthokeratology contact lenses in Spain: refractive and biometric changes.Invest Ophthalmol Vis Sci. 2012; 53: 5060-5065
- Higher spherical equivalent refractive errors is associated with slower axial elongation wearing orthokeratology.Contact Lens Anterior Eye. 2016; 39: 62-66
- Myopia control during orthokeratology lens wear in children using a novel study design.Ophthalmology. 2015; 122: 620-630
- Influence of overnight orthokeratology on axial elongation in childhood myopia.Invest Ophthalmol Vis Sci. 2011; 52: 2170-2174
- Long-term effect of overnight orthokeratology on axial length elongation in childhood myopia: a 5-year follow-up study.Invest Ophthalmol Vis Sci. 2012; 53: 3913-3919
- The longitudinal orthokeratology research in children (LORIC) in Hong Kong: a pilot study on refractive changes and myopic control.Curr Eye Res. 2005; 30: 71-80
- Studies using concentric ring bifocal and peripheral add multifocal contact lenses to slow myopia progression in school-aged children: a meta-analysis.Ophthalmic Physiol Opt. 2017; 37: 51-59
- Multifocal contact lens myopia control.Optom Vis Sci. 2013; 90: 1207-1214
- Central and peripheral corneal power change in myopic orthokeratology and its relationship with 2-year axial length change.Invest Ophthalmol Vis Sci. 2015; 56: 4514-4519
- Peripheral refraction in myopic patients after orthokeratology.Optom Vis Sci. 2010; 87: 323-329
- Association of axial length growth and topographic change in orthokeratology.Eye Contact Lens. 2018; 44: 292-298
- Interocular difference of peripheral refraction in anisomyopic eyes of schoolchildren.PLoS One. 2016; 11e0149110
- Under-correction of myopia enhances rather than inhibits myopia progression.Vision Res. 2002; 42: 2555-2559
- MillodotM, the possible effect of under-correction on myopic progression in children.Clin Exp Optom. 2006; : 315-321
Published online: December 19, 2019
Accepted: December 2, 2019
Received in revised form: November 29, 2019
Received: September 13, 2019
© 2019 Published by Elsevier Ltd on behalf of British Contact Lens Association.