Highlights
- •OrthoK lenses slow axial length growth in children with myopia.
- •There were no significant differences between four different brands/designs of lenses after two years of wear.
- •The spherical equivalent refraction and age at baseline are not the main influencing factors of OthorK in myopia control.
Abstract
Purpose
To compare axial length (AL) elongation in myopic children with four Orthokeratology
(OrthoK) lenses and spectacles.
Methods
The medical records of 266 patients (532 eyes) who were fitted with OrthoK lenses
or spectacles (control group) were reviewed. Data collection included baseline age,
gender, baseline objective sphere and cylinder, baseline flat and steep corneal meridian
power, corneal asphericity coefficient (Q value), AL at baseline and after 1-year,
and 2-years of OrthoK or spectacle wear analyzed using analysis of repeated measures
data ANOVA. Stepwise linear regressions between the changes in AL after 2 years relative
to baseline parameters were calculated for the OrthoK and control groups separately.
Results
The baseline subject parameters for each of the four OrthoK lenses were not statistically
different. Statistically significant differences between time points were found between
12- and 24- months (all P < 0.05). AL growth was slower in all OrthoK groups than in the control group (all
P < 0.05). AL grew 0.081±0.034 mm per year slightly less than average with Essence
compared to the Mouldway OrthoK group (P = 0.019). The coefficient of regression weakly expressed between the increases in
AL over 2-years study period and baseline spherical equivalent refraction was 0.065
in Essence, 0.079 in Euclid and 0.087 in Mouldway. The coefficient of regression was
also weakly between age and the increases AL over 2-years study period and baseline
age in all groups.
Conclusion
Different OrthoK lenses differ minimally in slowing axial elongation effectively in
myopic children during 2-years lens wear.
Keywords
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References
- Causes of vision loss worldwide, 1990-2010: a systematic analysis.Lancet Glob Health. 2013; 1: e339-e349
- Myopia: precedents for research in the twenty-first century.Clin Exp Ophthalmol. 2004; 32: 305-324
- Global prevalence of myopia and high myopia and temporal trends from 2000 through 2050.Ophthalmology. 2016; : 1036-1042
- Retardation of myopia in Orthokeratology (ROMIO) study: a 2-year randomized clinical trial.Invest Ophthalmol Vis Sci. 2012; 53: 7077-7085
- Long-term effect of overnight orthokeratology on axial length elongation in childhood myopia: a 5-year follow-up study.Invest Ophthalmol Vis Sci. 2012; 53: 3913-3919
- Orthokeratology and contact lens quality of life questionnaire (OCL-QoL).Eye Contact Lens. 2018; 44: 279-285
- Corneal reshaping and myopia progression.Br J Ophthalmol. 2009; 93: 1181-1185
- High myopia-partial reduction ortho-k: a 2-year randomized study.Optom Vis Sci. 2013; 90: 530-539
- Corneal response to short-term orthokeratology lens wear.Optom Vis Sci. 2003; 80: 200-206
- Corneal response to orthokeratology.Optom Vis Sci. 1998; 75: 791-799
- Local steepening in peripheral corneal curvature after corneal refractive therapy and LASIK.Optom Vis Sci. 2010; 87: 432-439
- Anterior and posterior corneal elevation after orthokeratology and standard and customized LASIK surgery.Eye Contact Lens. 2011; 37: 354-358
- Peripheral refraction in orthokeratology patients.Optom Vis Sci. 2006; 83: 641-648
- Peripheral refraction in myopic children wearing orthokeratology and gas-permeable lenses.Optom Vis Sci. 2011; 88: 476-482
- Relative peripheral refraction across 4 meridians after orthokeratology and LASIK surgery.Eye Vis (Lond). 2018; 5
- Efficacy comparison of 16 interventions for myopia control in children: a network meta-analysis.Ophthalmology. 2016; 123: 697-708
- Long-term efficacy of orthokeratology contact lens wear in controlling the progression of childhood myopia.Curr Eye Res. 2017; 42: 713-720
- Influence of overnight orthokeratology on axial elongation in childhood myopia.Invest Ophthalmol Vis Sci. 2011; 52: 2170-2174
- The control effect of orthokeratology on axial length elongation in Chinese children with myopia.BMC Ophthalmol. 2014; 14
- Lens Dk/t influences the clinical response in overnight orthokeratology.Optom Vis Sci. 2011; 88: 469-475
- Corneal refractive therapy with different lens materials, part 2: effect of oxygen transmissibility on corneal shape and optical characteristics.Optom Vis Sci. 2007; 84: 349-356
- Comparison of reverse-geometry lens designs for overnight orthokeratology.Optom Vis Sci. 2003; 80: 796-804
- The influence of different OK Lens designs on peripheral refraction.Optom Vis Sci. 2016; 93: 1112-1119
- Can manipulation of orthokeratology lens parameters modify peripheral refraction?.Optom Vis Sci. 2013; 90: 1237-1248
- Factors related to axial length elongation and myopia progression in orthokeratology practice.PLoS One. 2017; 12 (e0175913)
- Effects of orthokeratology on the progression of low to moderate myopia in Chinese children.BMC Ophthalmol. 2016; 16
- The development of myopia in Hong Kong children between the ages of 7 and 12 years: a five-year longitudinal study.Ophthalmic Physiol Opt. 1999; 19: 286-294
- Relationship of age, sex, and ethnicity with myopia progression and axial elongation in the correction of myopia evaluation trial.Arch Ophthalmol. 2005; 123: 977-987
- Factors related to the progression of myopia in Singaporean children.Optom Vis Sci. 2000; 77: 549-554
- Overnight orthokeratology is comparable with atropine in controlling myopia.BMC Ophthalmol. 2014; : 14
- Myopia control with orthokeratology contact lenses in Spain: refractive and biometric changes.Invest Ophthalmol Vis Sci. 2012; 53: 5060-5065
Article info
Publication history
Published online: December 04, 2019
Accepted:
November 26,
2019
Received in revised form:
November 15,
2019
Received:
July 9,
2019
Identification
Copyright
© 2019 British Contact Lens Association. Published by Elsevier Ltd. All rights reserved.