- •This contralateral study focused on the anisometropic children wearing ortho-k lens.
- •The eyes with greater myopia got less axial growth than the fellow eyes with less myopia in a 2-years’ study period.
- •Different myopia increase might be caused by different relative corneal refractive power change induced by ortho-k lens.
To investigate the effect of overnight orthokeratology (OK) lens wear on axial growth in anisometropic children.
The study involved 17 males and 12 females with an average age of 11.4 ± 2.9 years. Cycloplegic spherical equivalent error (SER) was −0.50D to −6.00D, and anisometropia ≥1.00D. The eyes with greater myopia were assigned to the G eye group and the fellow eyes with less myopia to the L eye group. All eyes were fitted with OK lenses. Axial length (AL) was measured at the beginning of the study and at 6-, 12-, 18-, and 24-month follow-up visits. Refractive error was measured at the beginning and at the 24-month visit. Linear mixed model analysis was used to evaluate the effect of time, group, and time*group on axial growth. Paired t test was used to compare the myopia increase over 24 months between the two groups.
Results:The mean baseline AL was 25.06 ± 0.61 mm for the G eyes and 24.48 ± 0.61 mm for the L eyes. After 24 months, AL had increased by 0.31 ± 0.23 mm in the G eye group and by 0.41 ± 0.31 mm in the L eye group. Axial growth of the L eyes was significantly greater than that of the G eyes (p = 0.006). The mean baseline myopia of the G eye and the L eye was −3.62 ± 1.27D [−5.75D to −1.75D] and −1.93 ± 1.02D [−4.00D to −0.50D] respectively. At 24 months, the increase in myopia in the G eyes was significantly less than that in the L eyes (−0.84 ± 0.63D vs, −1.21 ± 0.89D, p < 0.001).
Conclusions: In anisometropic children who wore OK lenses, axial growth was greater in the eye with less baseline myopia than in the fellow eye with greater baseline myopia after 2 years.
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Published online: March 22, 2019
Accepted: March 18, 2019
Received in revised form: March 7, 2019
Received: October 3, 2018
© 2019 British Contact Lens Association. Published by Elsevier Ltd. All rights reserved.