Highlights
- •Anterior scleral asymmetry was found to be significantly different between myopes and emmetropes.
- •Axial length and refractive power are highly correlated with the anterior scleral shape.
- •The more myopic the eye, the less asymmetric the anterior sclera.
Abstract
Purpose
To in-vivo quantify differences in anterior scleral shape between myopes and emmetropes
and relate them with axial length and refractive power.
Methods
Forty-two participants (84 eyes) were included in this study. Twenty-five participants
were categorised as emmetropes and seventeen participants were categorised as myopes.
The refractive state was measured monocularly using a closed window autorefractometer.
Axial length was acquired using an optical biometer and topographical data was obtained
using a non-contact corneo-scleral topographer. Anterior scleral asymmetry was calculated
from 3-dimensional data using a custom-made algorithm and further correlated to axial
length and refractive power. Right and left eyes were analysed independently.
Results
The anterior scleral shape was highly correlated with axial length (OS and OD: R = 0.76,
p < 0.001) and moderately correlated with refractive power (OS: R = 0.48, OD: R = 0.53,
both p < 0.01). The more myopic the eye, the less asymmetric the anterior sclera.
Conclusions
Both axial length and refractive power are well correlated with the anterior scleral
shape. The refractive state of each patient should therefore be taken into consideration
when analysing scleral shape when planning certain treatments or surgeries and when
fitting scleral contact lenses.
Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Contact Lens and Anterior EyeAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Nearly 1 billion myopes at risk of myopia‐related sight‐threatening conditions by 2050–time to act now.Clin Exp Optom. 2015; 98: 491-493
- Myopia: mechanisms, manifestations and management.Ophthalmic Physiol Opt. 2018; 38: 207-209
- Scleral remodelling in myopia and its manipulation: a review of recent advances in scleral strengthening and myopia control.Ann Eye Sci. 2018; 1
- Sclera as the target tissue in progressive myopia.Pomeranian J Life Sci. 2015; 2: 146-152
- The sclera and myopia.Exp Eye Res. 2006; 82: 185-200
- Rotation asymmetry of the human sclera.Acta Ophthalmol (Copenh). 2018; (in press)https://doi.org/10.1111/aos.13901)
- An analysis of anterior scleral shape and its role in the design and fitting of scleral contact lenses.Cont Lens Anterior Eye. 2018; 41: 205-213
- Scleral topography analysed by optical coherence tomography.Cont Lens Anterior Eye. 2017; 40: 242-247
- Age-related variations in the biomechanical properties of human sclera.J Mech Behav Biomed Mater. 2012; 16: 181-191
- Role of the sclera in the development and pathological complications of myopia.Prog Retin Eye Res. 2003; 22: 307-338
- Biomechanics of the sclera in myopia: extracellular and cellular factors.Optom Vis Sci. 2009; 86: E23-30
- An examination of the relation between intraocular pressure, fundal stretching and myopic pathology.Clin Exp Optom. 2016; 99: 113-119
- Scleral changes with accommodation.Ophthalmic Physiol Opt. 2017; 37: 263-274
- Experimental myopia increases and scleral crosslinking using genipin inhibits cyclic softening in the tree shrew sclera.Ophthalmic Physiol Opt. 2018; 38: 246-256
- Principles of operation, accuracy and precision of an eye surface profiler.Ophthalmic Physiol Opt. 2016; 36: 266-278
- Mean shape of the human limbus.J Cataract Refract Surg. 2017; 43: 667-672
- Scleral asymmetry as a potential predictor for scleral lens compression.Ophthalmic Physiol Opt. 2018; (In press)https://doi.org/10.1111/OPO.12587)
- The relationship between glaucoma and myopia: the Blue Mountains Eye Study.Ophthalmology. 1999; 106: 2010-2015
- High myopia and glaucoma susceptibility: the Beijing Eye Study.Ophthalmology. 2007; 114: 216-220
- Dimensions of the human sclera: thickness measurement and regional changes with axial length.Exp Eye Res. 2010; 90: 277-284
- Anterior eye surface changes following miniscleral contact lens wear.Cont Lens Anterior Eye. 2018; (In press)https://doi.org/10.1016/j.clae.2018.06.005
- The rigid lens renaissance: a surge in sclerals.Cont Lens Anterior Eye. 2018; 41: 139-143
- Scleral lenses: a literature review.Eye Contact Lens. 2015; 41: 3-11
- Modern scleral contact lenses: a review.Cont Lens Anterior Eye. 2014; 37: 240-250
- Scleral shape and its correlations with corneal astigmatism.Cornea. 2018; 37: 1047-1052
- Relationship of placido corneal topography data with scleral lens fitting parameters.Cont Lens Anterior Eye. 2018; (In press)https://doi.org/10.1016/j.clae.2018.07.005
- Corneo-scleral limbal changes following short-term soft contact lens wear.Cont Lens Anterior Eye. 2017; 40: 293-300
Article info
Publication history
Published online: November 01, 2018
Accepted:
October 26,
2018
Received in revised form:
October 26,
2018
Received:
September 18,
2018
Identification
Copyright
© 2018 British Contact Lens Association. Published by Elsevier Ltd. All rights reserved.