Abstract
Purpose
To assess the clinical and subjective performance of a one-step hydrogen peroxide
(H2O2) lens care system compared to a multi-purpose disinfecting system (MPDS) when used
with silicone hydrogel (SiH) lenses.
Methods
This was an eight-week, contralateral (lens type) clinical trial with a randomized,
cross-over (care system) design. The H2O2 system was Clear Care ((AO Sept Plus) CIBA VISION) and the MPDS was OPTI-FREE RepleniSH
(Alcon) and the SiH materials were lotrafilcon B (Air Optix; CIBA VISION) and senofilcon
A (Acuvue OASYS, Johnson & Johnson Vision Care). Investigators and subjects were masked
to lens care and lens type, respectively. Clinical variables and ocular health assessments
were conducted at a baseline, two-week and four-week visit for each cross-over phase.
Comfort, dryness and vision were rated on 0–100 scales. Wearing times and comfortable
wearing times were also recorded.
Results
Twenty-six subjects were enrolled: nine male, 17 female, mean age (±standard deviation)
31 ± 12 years (range 17–59 years) and 24 subjects completed the study. Clinical variables
showed no difference between solutions (all p > 0.05), however one subject exhibited solution-induced corneal staining with both lens
materials and the MPDS. There was no difference between solutions in subjective overall
ratings of comfort, dryness or vision (p > 0.05). The H2O2 resulted in longer reported comfortable wearing times than the MPDS (10.93 ± 1.71 vs 9.84 ± 1.47 h; repeated measures ANOVA, p < 0.01).
Conclusions
While both lens care systems performed well with the SiH lenses used, the H2O2 resulted in a longer reported comfortable wearing time then the MPDS.
Keywords
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Article info
Publication history
Published online: March 04, 2010
Footnotes
☆The authors have no commercial or financial interest in the products used in this study. Financial support for this study was provided by CIBA VISION.
Identification
Copyright
© 2010 British Contact Lens Association. Published by Elsevier Inc. All rights reserved.
