Contact Lens & Anterior Eye
Volume 33, Issue 2 , Pages 55-60 , April 2010

Validation of the 5-Item Dry Eye Questionnaire (DEQ-5): Discrimination across self-assessed severity and aqueous tear deficient dry eye diagnoses

  • Robin L. Chalmers

      Affiliations

    • School of Optometry, Indiana University, Bloomington, IN, USA
    • Corresponding Author InformationCorresponding author at: 2097 East Lake Rd, Atlanta, GA 30307, USA. Tel.: +1 404 687 9798.
    • ,
  • Carolyn G. Begley

      Affiliations

    • School of Optometry, Indiana University, Bloomington, IN, USA
    • ,
  • Barbara Caffery

      Affiliations

    • Yorkville Eye Clinic, Toronto, ON, Canada

References 

  1. Chalmers RL, Begley CG, Edrington T, et al. The agreement between self-assessment and clinician assessment of dry eye severity. Cornea. 2005;24(7):804–810
  2. Narayanan S, Miller WL, Prager TC, et al. The diagnosis and characteristics of moderate dry eye in non-contact lens wearers. Eye Contact Lens. 2005;31(3):96–104
  3. Bron AJ. Diagnosis of dry eye. Surv Ophthalmol. 2001;45(Suppl. 2):S221–S226
  4. Schein OD, Tielsch JM, Munoz B, et al. Relation between signs and symptoms of dry eye in the elderly. A population-based perspective. Ophthalmology. 1997;104(9):1395–1401
  5. Smith JA, Albeitz J, Begley C, et al. The epidemiology of dry eye disease: report of the epidemiology subcommittee of the international dry eye workShop (2007). Ocul Surf. 2007;5(2):93–107
  6. Lemp MA. Report of the national eye institute/industry workshop on clinical trials in dry eyes. CLAO J. 1995;21(4):221–232
  7. Lemp MA, Baudouin C, Baum J, et al. The definition and classification of dry eye disease: report of the Definition and Classification Subcommittee of the International Dry Eye WorkShop (2007). Ocul Surf. 2007;5(2):75–92
  8. Begley CG, Caffery B, Chalmers RL, Mitchell GL. Use of the dry eye questionnaire to measure symptoms of ocular irritation in patients with aqueous tear deficient dry eye. Cornea. 2002;21(7):664–670
  9. Begley CG, Chalmers RL, Abetz L, et al. The relationship between habitual patient-reported symptoms and clinical signs among patients with dry eye of varying severity. Invest Ophthalmol Vis Sci. 2003;44(11):4753–4761
  10. Nichols KK, Nichols JJ, Mph M, Mitchell GL. The lack of association between signs and symptoms in patients with dry eye disease. Cornea. 2004;23(8):762–770
  11. Hay EM, Thomas E, Pal B, et al. Weak association between subjective symptoms or and objective testing for dry eyes and dry mouth: results from a population based study. Ann Rheum Dis. 1998;57(1):20–24
  12. Bjerrum KB. Test and symptoms in keratoconjunctivitis sicca and their correlation. Acta Ophthalmol Scand. 1996;74(5):436–441
  13. Doughty MJ, Fonn D, Richter D, et al. A patient questionnaire approach to estimating the prevalence of dry eye symptoms in patients presenting to optometric practices across Canada. Optom Vis Sci. 1997;74(8):624–631
  14. Schein OD, Munoz B, Tielsch JM, et al. Prevalence of dry eye among the elderly. Am J Ophthalmol. 1997;124(6):723–728
  15. Schaumberg DA, Sullivan DA, Buring JE, Dana MR. Prevalence of dry eye syndrome among US women. Am J Ophthalmol. 2003;136(2):318–326
  16. Gulati A, Sullivan R, Buring JE, et al. Validation and repeatability of a short questionnaire for dry eye syndrome. Am J Ophthalmol. 2006;142(1):125–131
  17. Miljanovic B, Dana R, Sullivan DA, Schaumberg DA. Impact of dry eye syndrome on vision-related quality of life. Am J Ophthalmol. 2007;143(3):409–415
  18. Miljanovic B, Trivedi KA, Dana MR, et al. Relation between dietary n-3 and n-6 fatty acids and clinically diagnosed dry eye syndrome in women. Am J Clin Nutr. 2005;82(4):887–893
  19. Schaumberg DA, Dana R, Buring JE, Sullivan DA. Prevalence of dry eye disease among US men: estimates from the Physicians’ Health Studies. Arch Ophthalmol. 2009;127(6):763–768
  20. Chia EM, Mitchell P, Rochtchina E, et al. Prevalence and associations of dry eye syndrome in an older population: the Blue Mountains Eye Study. Clin Experiment Ophthalmol. 2003;31(3):229–232
  21. McMonnies CW, Ho A. Patient history in screening for dry eye conditions. J Am Optom Assoc. 1987;58(4):296–301
  22. Schiffman RM, Christianson MD, Jacobsen G, et al. Reliability and validity of the Ocular Surface Disease Index. Arch Ophthalmol. 2000;118(5):615–621
  23. Rajagopalan K, Abetz L, Mertzanis P, et al. Comparing the discriminative validity of two generic and one disease-specific health-related quality of life measures in a sample of patients with dry eye. Value Health. 2005;8(2):168–174
  24. Vitale S, Goodman LA, Reed GF, Smith JA. Comparison of the NEI-VFQ and OSDI questionnaires in patients with Sjogren's syndrome-related dry eye. Health Qual Life Outcomes. 2004;2(1):44
  25. Liu H, Begley C, Chen M, et al. A link between tear instability and hyperosmolarity in dry eye. Invest Ophthalmol Vis Sci. 2009;50(8):3671–3679
  26. Chalmers R, Begley C. Repeatability of habitual symptoms as measured by the dry eye questionnaire (DEQ). ARVO Abstract 2004:3455.
  27. Chalmers R. Does time of administration of the Dry Eye Questionnaire (DEQ) influence frequency or intensity of habitual symptom responses? Br Cont Lens Assoc Meet 2008.
  28. Caffery B, Joyce E, Heynen ML, et al. MUC16 expression in Sjogren's syndrome, KCS, and control subjects. Mol Vis. 2008;14:2547–2555
  29. Fox RI, Saito I. Criteria for diagnosis of Sjogren's syndrome. Rheum Dis Clin North Am. 1994;20(2):391–407
  30. Vitali C, Moutsopoulos HM, Bombardieri S. The European Community Study Group on diagnostic criteria for Sjogren's syndrome. Sensitivity and specificity of tests for ocular and oral involvement in Sjogren's syndrome. Ann Rheum Dis. 1994;53(10):637–647
  31. Fairchild C, Chalmers R, Begley C. Clinically important difference in dry eye: change in IDEEL-symptom bother. Optom Vis Sci. 2008;85(8):699–707
  32. Redelmeier D, Guyatt G, Goldstein R. Assessing the minimal important difference in symptoms: a comparison of two techniques. J Clin Epidemiol. 1996;49(11):1215–1219
  33. Bron AJ, Abelson MB, Smith JA, et al. Methodologies to diagnose and monitor dry eye disease: report of the diagnostic metholology subcommittee of the international dry eye workshop (2007). Ocul Surf. 2007;5(2):108–152
  34. Kramer MS. Clinical epidemiology and biostatistics: a primer for clinical investigators and decision-makers. Berlin: Springer-Verlag; 1988;[chapter 16]
  35. Moss SE, Klein R, Klein BE. Incidence of dry eye in an older population. Arch Ophthalmol. 2004;122(3):369–373
  36. McCarty CA, Bansal AK, Livingston PM, et al. The epidemiology of dry eye in Melbourne, Australia. Ophthalmology. 1998;105(6):1114–1119
  37. Bandeen-Roche K, Munoz B, Tielsch JM, et al. Self-reported assessment of dry eye in a population-based setting. Invest Ophthalmol Vis Sci. 1997;38(12):2469–2475
  38. Himebaugh NL, Begley CG, Bradley A, Wilkinson JA. Blinking and tear break-up during four visual tasks. Optom Vis Sci. 2009;86(2):E106–E114
  39. Wolkoff P. Healthy” eye in office-like environments. Environ Int. 2008;34(8):1204–1214
  40. Brasche S, Bullinger M, Petrovitch A, et al. Self-reported eye symptoms and related diagnostic findings—comparison of risk factor profiles. Indoor Air. 2005;15(Suppl. 10):56–64
  41. Backman H, Haghighat F. Indoor-air quality and ocular discomfort. J Am Optom Assoc. 1999;70(5):309–316
  42. Gupta N, Prasad I, Himashree G, D'Souza P. Prevalence of dry eye at high altitude: a case controlled comparative study. High Alt Med Biol. 2008;9(4):327–334
  43. Gonzalez-Meijome JM, Parafita MA, Yebra-Pimentel E, Almeida JB. Symptoms in a population of contact lens and noncontact lens wearers under different environmental conditions. Optom Vis Sci. 2007;84(4):296–302

PII: S1367-0484(09)00182-9

doi: 10.1016/j.clae.2009.12.010

Contact Lens & Anterior Eye
Volume 33, Issue 2 , Pages 55-60 , April 2010

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