Contact Lens & Anterior Eye
Volume 33, Issue 2 , Pages 76-82 , April 2010

Effect of castor oil emulsion eyedrops on tear film composition and stability

  • Cécile Maïssa

      Affiliations

    • OTG Research & Consultancy, London, UK
    • Corresponding Author InformationCorresponding author at: OTG Research & Consultancy, Optometric Technology Group, 66 Buckingham Gate, London SW1E 6AU, UK. Tel.: +44 2072224224; fax: +44 2072224246.
    • ,
  • Michel Guillon

      Affiliations

    • OTG Research & Consultancy, London, UK
    • ,
  • Peter Simmons

      Affiliations

    • Allergan, Irvine, CA, USA
    • ,
  • Joseph Vehige

      Affiliations

    • Allergan, Irvine, CA, USA

References 

  1. Lemp MA. Report of the National Eye Institute/Industry Workshop on Clinical trials in dry eyes. CLAO J. 1995;21(4):221–232
  2. Hikichi T, Yoshida A, Fukui Y, Hamano T, Ri M, Araki K, et al. Prevalence of dry eye in Japanese eye centers. Graefes Arch Clin Exp Ophthalmol. 1995;233(9):555–558
  3. Doughty MJ, Fonn D, Richter D, Simpson T. , Caffery B, Gordon K. A patient questionnaire approach of dry eye symptoms in patients presenting to optometric practices across Canada. Optom Vis Sci. 1997;74(8):624–631
  4. Bandeen-Roche K, Muñoz B, Tielsch JM, West SK, Schein OD. Self-reported assessment of dry eye in a population-based setting. Invest Ophthalmol Vis Sci. 1997;38(12):2469–2475
  5. Shimmura S, Shimazaki J, Tsubota K. Results of a population-based questionnaire on the symptoms and lifestyles associated with dry eye. Cornea. 1999;18(4):408–411
  6. Moss SE, Klein R, Klein BE. Prevalence and risk factors for dry eye syndrome. Arch Ophthalmol. 2000;118:1264–1268
  7. Lee AJ, Lee J, Saw SM, Gazzard G, Koh D, Widjaja D, et al. Prevalence and risk factors associated with dry eye symptoms: a population based study in Indonesia. Br J Ophthalmol. 2002;86(12):1347–1351
  8. Lin PY, Cheng CY, Hsu WM, Tsai SY, Lin MW, Liu JH, et al. Association between symptoms and signs of dry eye among an elderly Chinese population in Taiwan: the Shihpai Eye Study. Invest Ophthalmol Vis Sci. 2005;46(5):1593–1598
  9. Lekhanont K, Rojanaporn D, Chuck RS, Vongthongsri A. Prevalence of dry eye in Bangkok, Thailand. Cornea. 2006;25(10):1162–1167
  10. McCarty CA, Bansal AK, Livingston PM, Stanislavsky YL, Taylor HR. The epidemiology of dry eye in Melbourne, Australia. Ophthalmology. 1998;105:1114–1119
  11. Guillon M, Maissa C. Dry eye symptomatology of soft contact lens wearers and nonwearers. Optom Vis Sci. 2005;82(9):829–834
  12. Nelson JD, Helms H, Fiscella R, Southwell Y, Hirsch JD. A new look at dry eye disease and its treatment. Adv Ther. 2000;17:84–93
  13. American Academy of Ophthalmology . State-of-the-art management of chronic dry eye: proceedings from a scientific roundtable. American Academy of Ophthalmology; 2006;www.aao.org
  14. Lemp MA. Management of dry eye disease. Am J Manag Care. 2008;14:S88–S101
  15. Hom M, Simmons P. Understanding emulsion eyedrop technology. Rev Contact Lenses. 2003;124–126
  16. Sall K, Stevenson OD, Mundorf TK, Reis BL. Two multi-center, randomized studies of the efficacy and safety of cyclosporine ophthalmic emulsion in moderate or severe dry eye disease. Ophthalmology. 2000;107:631–639
  17. Stevenson D, Tauber J, Reis BL. Efficacy and safety of cyclosporin A ophthalmic emulsion in the treatment of moderate-to-severe dry eye disease: a dose-ranging, randomized trial. The cyclosporin A phase 2 study group. Ophthalmology. 2000;107:967–974
  18. Vehige J, Carlisle C, Felix C, Simmons PA, Stoecker J. Clinical trial results of a new emulsion-based dry eye treatment. Invest Ophthalmol Vis Sci. 2003;44:2449;ARVO E-Abstract
  19. Di Pascuale MA, Goto E, Tseng SC. Sequential changes of lipid tear film after instillation of a single drop of a new emulsion eye drop in dry eye patients. Ophthalmology. 2004;111(4):783–791
  20. Khanal S, Tomlinson A, Pearce EI. Efficacy of an emulsion eye drop in the management of mild to moderate dry eyes. Invest Ophthalmol Vis Sci. 2005;46:2038;E-Abstract
  21. Goto E, Shimazaki J, Monden Y, Takano Y, Yagi Y. Low concentration homogenized castor oil eye drops for non inflamed obstructive meibomian gland dysfunction. Ophthalmology. 2002;109(11):2030–2035
  22. Guillon M, Allary JC, Guillon JP, Orsborn G. Clinical management of regular replacement. Part 1. Selection of replacement frequency. ICLC. 1992;19:104–120
  23. Guillon JP, Guillon M. The role of tears in contact lens performance and its measurement. In:  Ruben M,  Guillon M editor. Contact lens practice. 21:London: Chapman & Hall Medical; 1994;p. 453–483
  24. Du toit R, Pritchard N, Heffernan S, Simpson T, Fonn D. A comparison of three different scales for rating contact lens handling. Optom Vis Sci. 2002;79:313–320
  25. Bailey IL, Bullimore MA, Raasch TW, Taylor HR. Clinical grading and the effects of scaling. Invest Ophthalmol Vis Sci. 1991;32:422–432

☆ The investigation was sponsored via a grant from Allergan Inc..

PII: S1367-0484(09)00150-7

doi: 10.1016/j.clae.2009.10.005

Contact Lens & Anterior Eye
Volume 33, Issue 2 , Pages 76-82 , April 2010

Article Tools

* Image Usage & Resolution