Contact Lens & Anterior Eye
Volume 30, Issue 2 , Pages 94-107 , May 2007

Current concepts: Contact lens related Pseudomonas keratitis

  • Danielle M. Robertson

      Affiliations

    • Department of Ophthalmology, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390-9057, USA
    • ,
  • W. Matthew Petroll

      Affiliations

    • Department of Ophthalmology, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390-9057, USA
    • ,
  • James V. Jester

      Affiliations

    • The Eye Institute, Department of Ophthalmology, The University of California at Irvine, Irvine, CA, USA
    • ,
  • H. Dwight Cavanagh

      Affiliations

    • Department of Ophthalmology, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390-9057, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 214 648 8074; fax: +1 214 648 9061.

References 

  1. Fleiszig SMJ, Efron N, Pier GB. Extended contact lens wear enhances Pseudomonas aeruginosa adherence to human corneal epithelium. Invest Ophthalmol Vis Sci. 1992;33:2908–2915
  2. Cheng KH, Leung SL, Hoekman HW, et al. Incidence of contact-lens-associated microbial keratitis and its related morbidity. Lancet. 1999;354:181–185
  3. Fleiszig SM, Zaidi TS, Fletcher EL, Preston MJ, Pier GB. Pseudomonas aeruginosa invades corneal epithelial cells during experimental infection. Infect Immun. 1994;62:3485–3493
  4. Yamamoto N, Yamamoto N, Petroll WM, Cavanagh HD, Jester JV. Internalization of Pseudomonas aeruginosa is mediated by lipid rafts in contact lens-wearing rabbit and cultured human corenal epithelial cells. Invest Ophthalmol Vis Sci. 2005;46:1348–1355
  5. Yamamoto N, Yamamoto N, Jester JV, Petroll WM, Cavanagh HD. Prolonged Hypoxia induces lipid raft formation and increases Pseudomonas internalization in vivo after contact lens wear and lid closure. Eye Contact Lens. 2006;32:114–120
  6. Yamamoto N, Yamamoto N, Petroll WM, Jester JV, Cavanagh HD. Regulation of Pseudomonas aeruginosa internalization after contact lens wear in vivo and in serum-free culture by ocular surface cells. Invest Ophthalmol Vis Sci. 2006;47:3430–3440
  7. Simons K, Ikonen E. Functional rafts in cell membrane. Nature. 1997;387:569–572
  8. Guo B, Kato RM, Garcia-Lloret M, Wahl MI, Rawlings DJ. Engagement of the human pre-β cell receptor generates a lipid raft dependent calcium signaling complex. Immunity. 2000;13:243–253
  9. Janes PW, Ley SC, Magee Al. Aggregation of lipid rafts accompanies signaling via the t cell antigen receptor. J Cell Biol. 1999;147:447–461
  10. Letinger B, Hogg N. The involvement of lipid rafts in the regulation of integrin function. J Cell Sci. 2002;115:963–972
  11. Grassme H, Jendrossek V, Riehle A, et al. Host defense against Pseudomonas aeruginosa requires ceramide-rich membrane rafts. Nat Med. 2003;9:322–330
  12. Imayasu M, Petroll WM, Jester JV, Patel SK, Ohashi J, Cavanagh HD. The relation between contact lens oxygen transmissibility and binding of Pseudomonas to the cornea after overnight wear. Ophthalmology. 1994;101:371–388
  13. Zaidi T, Mowrey-McKee M, Pier GB. Hypoxia increases corneal cell expression of CFTR leading to increased Pseudomonas aeruginosa binding, internalization, and initiation of inflammation. Invest Ophthalmol Vis Sci. 2004;45:4066–4074
  14. Zaidi TS, Lyczak J, Preston M, Pier GB. Cystic fibrosis transmembrane conductance regulator-mediated corneal epithelial cell ingestion of Pseudomonas aeruginosa is a key component in the pathogenesis of experimental murine keratitis. Infect Immun. 1999;67:1481–1492
  15. Robertson DM, Li L, Fisher S, et al. Characterization of growth and differentiation in a telomerase-immortalized human corneal epithelial cell line. Invest Ophthalmol Vis Sci. 2005;46:470–478
  16. Jester JV, Huang J, Fisher S, et al. Myofibroblast differences of normal human keratocytes and hTERT, extended-life human corneal fibroblasts. Invest Ophthalmol Vis Sci. 2003;44:1850–1858
  17. Keller P, Simons K. Cholesterol is required for surface transport of influenza virus hemagglution. J Cell Biol. 1998;140:1357–1367
  18. Schnitzer Je, Oh P, Pinney E, Allard J. Filipin-sensitive cavcolac-mediated transport in endothelium: reduced transcytosis, scavenger endocytosis, and capillary permeability of select macromolecules. J Cell Biol. 1994;127:1217–1232
  19. Stuart ES, Webley WC, Norkin LC. lipid rafts, caveolae, caveolin-l, and entry by Chlamydiae into host cells. Exp Cell Res. 2006;287:67–78
  20. Grassme H, Jendrossek V, Richle A, et al. Host defense against Pseudomonas aeruginosa requires ceramide-rich membrane rafts. Nat Med. 2003;9:322–330
  21. Szliter EA, Barrett RP, Gabriel MM, Zhang Y, Hazlett LD. Pseudomonas aeruginosa-induced inflammation in the rat extended-wear contact lens model. Eye Contact Lens. 2006;32:12–18
  22. Ren H, Petroll WM, Jester JV, et al. Adherence of Pseudomonas aeruginosa to shed rabbit corneal epithelial cells after overnight wear of contact lenses. CLAO J. 1997;23:63–68
  23. Ren DH, Petroll WM, Jester JV, et al. The relationship between contact lens oxygen permeability and binding of Pseudomonas aeruginosa to human corneal epithelial cells and overnight and extended wear. CLAO J. 1999;25:80–100
  24. Ren DH, Petroll WM, Jester JV, Ho-Fan J, Cavanagh HD. Short-term hypoxia downregulates epithelial cell desquamation in vivo, but does not increase Pseudomonas aeruginosa adherence to exfoliated human corneal epithelial cells. CLAO J. 1999;25:73–79
  25. Ladage PM, Yamamoto K, Ren DH, et al. Effects of rigid and soft contact lens daily wear on corneal epithelium, tear lactate dehydrogenase, and bacterial binding of exfoliated epithelial cells. Ophthalmology. 2001;108:1279–1288
  26. Ren DH, Yamamoto K, Ladage PM, et al. Adaptive effects of 30-night wear of hyper-O(2) transmissible contact lenses on bacterial binding and corneal epithelium: a 1-year clinical trial. Ophthalmology. 2002;109:27–40
  27. Cavanagh HD, Ladage PM, Li SL, et al. Effects of daily and overnight wear of a novel hyper oxygen-transmissible soft contact lens on bacterial binding and corneal epithelium: a 13-month clinical trial. Ophthalmology. 2002;109:1957–1969
  28. Benjamin WJ. EOP and Dk/L: The quest for hypertransmissibility. J Am Optom Assoc. 1993;64:196–200

☆ Presented in part as a keynote address at the British Contact Lens Association Annual Meeting, 21 May 2006, Birmingham, England (UK) (HDC).

PII: S1367-0484(06)00134-2

doi: 10.1016/j.clae.2006.10.001

Contact Lens & Anterior Eye
Volume 30, Issue 2 , Pages 94-107 , May 2007

Article Tools

* Image Usage & Resolution