Contact Lens & Anterior Eye
Volume 28, Issue 4 , Pages 181-184, December 2005

Subconjunctival cyst-like formations following impression cytology

  • Sruthi Srinivasan

      Affiliations

    • Centre for Contact Lens Research, School of Optometry, University of Waterloo, 200, University Avenue West, Waterloo, Ont., Canada N2L 3G1
    • Corresponding Author InformationCorresponding author. Tel.: +1 519 888 4567x7312; fax: +1 519 884 8769.
    • ,
  • Elizabeth Joyce

      Affiliations

    • Centre for Contact Lens Research, School of Optometry, University of Waterloo, 200, University Avenue West, Waterloo, Ont., Canada N2L 3G1
    • ,
  • Lyndon W. Jones

      Affiliations

    • Centre for Contact Lens Research, School of Optometry, University of Waterloo, 200, University Avenue West, Waterloo, Ont., Canada N2L 3G1
    • ,
  • Michelle Senchyna

      Affiliations

    • Alcon Research Ltd., 6201 South Freeway, Fort Worth, TX 76134-2099, USA

published online 22 November 2005.

Abstract 

Purpose

To report a case of an unusual adverse event subsequent to undertaking Conjunctival Impression Cytology (CIC).

Methods

CIC was undertaken on a 54-year-old healthy Caucasian female, using a 10mm Millipore™ membrane on the bulbar conjunctiva. Prior to the CIC procedure, two drops of topical proparacaine (Alcaine®) were instilled and following the procedure two drops of artificial tears (GenTeal®) were administered.

Results

The subject reported excessive bulbar conjunctival hyperaemia in the left eye 5min postprocedure, with no marked pain or discomfort. Slitlamp biomicroscopic evaluation revealed several “bubbles” or cystic formations trapped underneath the conjunctival tissue, in association with moderate to severe bulbar conjunctival redness. These cysts began to regress fairly rapidly and completely disappeared within 1h.

Conclusion

CIC is a useful tool for studying the ocular surface; however, care should be taken while performing this mildly invasive procedure. This is the first report of bubble formation in the conjunctiva following CIC. Subjects should be advised about the short term redness and discomfort that could occur following CIC.

Keywords: Impression cytology, Conjunctiva, Hyperaemia, Artificial tears, Conjunctival cyst

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PII: S1367-0484(05)00082-2

doi:10.1016/j.clae.2005.10.003

Contact Lens & Anterior Eye
Volume 28, Issue 4 , Pages 181-184, December 2005

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